Selected research
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Development of a Safety Surveillance Plan for The Academic Medicine Sponsor Performing First in Human Cellular Therapy Clinical Trials: A Report from the Consortium for Pediatric Cellular Immunotherapy.
Transplantation and cellular therapy
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Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies.
Pediatric blood & cancer
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A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Clinical trials
Project: Every Child for Younger Patients With Cancer
The number of patients who agree to be in the Biobanking part of the study and have leftover tumor tissue and some normal blood, bone marrow, or other tissue saved for future research.
Recruiting
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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusi...
The Kaplan-Meier method will be used to estimate 3-year FFS along with 80% log-minus-log transformed confidence limits for very low risk (VLR) patients.
Recruiting
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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL...
Improvement in 5-year disease-free survival (DFS) with modified Berlin-Frankfurt-Münster (mBFM) chemotherapy without delayed intensification (DI) part 2 but with inotuzumab ozogamicin, versus full mBFM chemotherapy backbone includ...
Recruiting
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A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Dia...
Will be assessed in SR-High patients and SR-Avg B-ALL patients who are negative for MRD by flow cytometry but have detectable or indeterminate MRD as measured by high throughput sequencing (HTS) at end of induction (EOI), and pati...
Recruiting
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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute ...
Summary statistics will be used to characterize the study populations on CHC outcomes. Quantitative data (number of comorbidities) will be summarized using descriptive statistics and correlational techniques. Will use pooled logis...
Recruiting
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Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or ...
For patients assigned to arms A and B, the investigators will separately estimate the proportion of patients who experience conjugated hyperbilirubinemia > 3mg/dL during induction chemotherapy by arm along with corresponding 95% c...
Recruiting
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Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philad...
Three-year DFS and 95% confidence intervals (CI) of SR Ph+ ALL patients treated continuous imatinib mesylate with high risk Children's Oncology Group (COG)-ALL chemotherapy backbone or more intensive European (Es)PhALL chemotherap...
Recruiting
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Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Re...
Response rates will be calculated as the percent of evaluable patients who are responders, and confidence intervals will be constructed using the Wilson score interval method.
Recruiting
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Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and...
Will report the proportion of patients with a serologic response to a protocol-approved COVID-19 vaccine, captured using a test for SARS-CoV-2-specific antibodies via immunoassay, and will report a corresponding 95% confidence int...
Recruiting
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A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk...
Will be estimated using the Kaplan-Meier method and will be compared between the two regimens using a log-rank test.
Recruiting
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Where I see patients (5)
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